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Found 89 Enz. Inhib. hit(s) with Target = '3-hydroxyacyl-[acyl-carrier-protein] dehydratase'
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50135169((-)-Catechin gallate | (2S,3R)-2-(3,4-dihydroxyphe...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50329257(2-Hexadecynoic acid | CHEMBL1269411)
Affinity DataKi:  4.80E+3nMAssay Description:Competitive inhibition of Plasmodium falciparum FabZ using crotonyl-CoA as substrate by Michaelis-Menten steady state analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataKi:  1.15E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Affinity DataIC50:  400nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50135169((-)-Catechin gallate | (2S,3R)-2-(3,4-dihydroxyphe...)
Affinity DataIC50:  400nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50153015((-)-Epicatechin-3-gallate | (-)-epicatechin 3-O-ga...)
Affinity DataIC50:  400nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50236531((-)-gallocatechin gallate | (2R,3S)-5,7-dihydroxy-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31965(carbohydrazide derivative, 5h)
Affinity DataIC50:  860nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31930(carbohydrazide derivative, 3m)
Affinity DataIC50:  1.42E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31927(carbohydrazide derivative, 3j)
Affinity DataIC50:  1.50E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31934(carbohydrazide derivative, 3q)
Affinity DataIC50:  1.52E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31926(carbohydrazide derivative, 3i)
Affinity DataIC50:  1.52E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31964(carbohydrazide derivative, 5g)
Affinity DataIC50:  1.97E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31928(carbohydrazide derivative, 3k)
Affinity DataIC50:  1.98E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31960(carbohydrazide derivative, 5c)
Affinity DataIC50:  2.13E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31967(carbohydrazide derivative, 5j)
Affinity DataIC50:  3.55E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31963(carbohydrazide derivative, 5f)
Affinity DataIC50:  3.75E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175](Yersinia pestis)
Brookhaven National Laboratory

LigandPNGBDBM24777(5-hydroxy-1,4-dihydronaphthalene-1,4-dione | 5-hyd...)
Affinity DataIC50:  5.30E+3nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Francisella tularensis)
Brookhaven National Laboratory

LigandPNGBDBM24777(5-hydroxy-1,4-dihydronaphthalene-1,4-dione | 5-hyd...)
Affinity DataIC50:  5.40E+3nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175](Yersinia pestis)
Brookhaven National Laboratory

LigandPNGBDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Affinity DataIC50:  6.10E+3nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31925(carbohydrazide derivative, 3h)
Affinity DataIC50:  6.43E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Francisella tularensis)
Brookhaven National Laboratory

LigandPNGBDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Affinity DataIC50:  7.70E+3nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31966(carbohydrazide derivative, 5i)
Affinity DataIC50:  8.77E+3nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31931(carbohydrazide derivative, 3n)
Affinity DataIC50:  9.92E+3nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50440622(CHEMBL2426556)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31961(carbohydrazide derivative, 5d)
Affinity DataIC50:  1.28E+4nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175](Yersinia pestis)
Brookhaven National Laboratory

LigandPNGBDBM50056922(1,4-Dihydroxy-10-methoxy-5,8-dimethyl-3,7-dioxo-1,...)
Affinity DataIC50:  1.30E+4nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50440621(CHEMBL2426554)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50440620(CHEMBL2426552)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Francisella tularensis)
Brookhaven National Laboratory

LigandPNGBDBM50056922(1,4-Dihydroxy-10-methoxy-5,8-dimethyl-3,7-dioxo-1,...)
Affinity DataIC50:  2.78E+4nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50440619(CHEMBL2426555)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175](Yersinia pestis)
Brookhaven National Laboratory

LigandPNGBDBM11318(1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...)
Affinity DataIC50:  2.97E+4nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM23420(7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50081950(6-Hydroxy-2-phenyl-chromen-4-one | 6-Hydroxyflavon...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31917(carbohydrazide derivative, 1)
Affinity DataIC50:  3.98E+4nMpH: 8.0 T: 2°CAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50187663(5,7-dimethoxy-8-methyl-flavanone | CHEMBL207954)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of FabZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31959(carbohydrazide derivative, 5b)
Affinity DataIC50:  4.27E+4nMAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Francisella tularensis)
Brookhaven National Laboratory

LigandPNGBDBM11318(1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...)
Affinity DataIC50:  4.31E+4nMpH: 7.0 T: 2°CAssay Description:The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50440627(CHEMBL2426553)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50440626(CHEMBL2426548)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50440625(CHEMBL2426549)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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