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Found
1
Enz. Inhib. hit(s) with Target = 'Ataxin-1' and Ligand = 'BDBM446116'
Target
Ataxin-1
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM446116
((3aR,8aS)-3,5-dichlorobenzyl 2-(1H-benzo[d][1,2,3]...)
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Affinity Data
IC50: 4nM
Assay Description:
ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...
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Target Info
PDB
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Ligand Info
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PDB
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Details
US Patent
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