Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50336646'
TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50336646(7-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4...)
Affinity DataEC50:  77nMAssay Description:Agonist activity at human FXR LBD iexpressed in monkey CV-1 cells assessed as transactivation of luciferase reporter gene expressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50336646(7-[4-({[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human FXR LBD assessed as SRC1 peptide recruitment by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed