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Found 2 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 4' and Ligand = 'BDBM50270038'
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50270038(CHEMBL4062223)
Affinity DataIC50:  3.70nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50270038(CHEMBL4062223)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at CXCR4 in human CCRF-CEM cells assessed as induction of Ca2+ flux measured for 90 secs by calcium dye-based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed