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Found 3 Enz. Inhib. hit(s) with Target = 'DNA repair protein RAD51 homolog 1' and Ligand = 'BDBM50527107'
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50527107(CHEMBL4450955)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to recombinant His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50527107(CHEMBL4450955)
Affinity DataEC50:  1.84E+4nMAssay Description:Inhibition of RAD51 in human BxPC3 cells assessed as reduction in homologous recombination incubated for 5 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50527107(CHEMBL4450955)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed