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Found 3 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50049904'
TargetDihydrofolate reductase(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50049904(7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine | CHEMBL3...)
Affinity DataKi:  1nMAssay Description:Competitive inhibition of human recombinant DHFR preincubated for 2 mins followed by substrate addition in presence of dihydrofolateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Candida albicans)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049904(7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine | CHEMBL3...)
Affinity DataKi:  23nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50049904(7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine | CHEMBL3...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant Dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed