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Found 2 Enz. Inhib. hit(s) with Target = 'Envelope glycoprotein gp160' and Ligand = 'BDBM461121'
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Gilead Sciences

US Patent
LigandPNGBDBM461121(US10774053, Compound 341 | US11352329, COMPD # 341)
Affinity DataIC50:  3.20nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Gilead Sciences

US Patent
LigandPNGBDBM461121(US10774053, Compound 341 | US11352329, COMPD # 341)
Affinity DataEC50:  8.54nMAssay Description:Assay protocol is identical to that described for the MT-4 antiviral assay with the following changes: Each drug is run in 2 series of quadruplicates...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent