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Found 4 Enz. Inhib. hit(s) with Target = 'Fascin' and Ligand = 'BDBM350100'
TargetFascin(Homo sapiens (human))
Cornell University

US Patent
LigandPNGBDBM350100(5-(3,4-dichlorobenzyl)-1- (S,S,-dioxo- tetrahydrot...)
Affinity DataIC50:  734nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
TargetFascin(Homo sapiens (human))
Cornell University

US Patent
LigandPNGBDBM350100(5-(3,4-dichlorobenzyl)-1- (S,S,-dioxo- tetrahydrot...)
Affinity DataIC50:  734nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
TargetFascin(Homo sapiens (human))
Cornell University

US Patent
LigandPNGBDBM350100(5-(3,4-dichlorobenzyl)-1- (S,S,-dioxo- tetrahydrot...)
Affinity DataIC50:  6.76E+4nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
TargetFascin(Homo sapiens (human))
Cornell University

US Patent
LigandPNGBDBM350100(5-(3,4-dichlorobenzyl)-1- (S,S,-dioxo- tetrahydrot...)
Affinity DataKd:  2.93E+4nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair