Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50256128'
TargetFatty acid synthase(Rattus norvegicus)
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of FASN in human A375 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of human recombinant FASN thioesterase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed