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Found 5 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50121210'
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human KDAC8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC8 (unknown origin) using Fluoro-Substrate Peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC8 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed