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Found 2 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM319573'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319573(4-(((2S,3R)-3-ethyl-5-oxopyrrolidin-2-yl)methoxy)-...)
Affinity DataIC50:  2.70nMAssay Description:This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319573(4-(((2S,3R)-3-ethyl-5-oxopyrrolidin-2-yl)methoxy)-...)
Affinity DataIC50:  47nMAssay Description:This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent