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Found 5 Enz. Inhib. hit(s) with Target = 'Lanosterol synthase' and Ligand = 'BDBM50055642'
TargetLanosterol synthase(Rattus norvegicus)
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055642(2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...)
Affinity DataKi:  180nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055642(2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...)
Affinity DataKi:  1.40E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055642(2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...)
Affinity DataIC50:  2.30nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055642(2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...)
Affinity DataIC50:  260nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50055642(2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed