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Found 8 Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM50445346'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  14nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  32nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 10...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  35nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  35nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  55nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 10...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50:  13nMAssay Description:Inhibition of LSD1 (unknown origin) using dimethyl K4 peptide as substrate assessed as resorufin level by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50:  13nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed