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Found 3 Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor' and Ligand = 'BDBM50298008'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298008(3-(3-(3-(3-fluoro-4-methoxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298008(3-(3-(3-(3-fluoro-4-methoxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298008(3-(3-(3-(3-fluoro-4-methoxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed