Found 13 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM21123' TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor in Wistar rat brain membrane after 1 hr by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 2.80nM ΔG°: -48.8kJ/mole EC50: 13nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cells assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cells by radioligand binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataEC50: 10.5nMAssay Description:Agonist activity at rat mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataEC50: 10.5nMAssay Description:Agonist activity at rat mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataEC50: 154nMAssay Description:Agonist activity at MOR in Wistar rat brain membranes after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
