Found 5 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50009146' TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences
Curated by ChEMBL
National Institute Of Environmental Health Sciences
Curated by ChEMBL
Affinity DataKi: 5.85E+3nMAssay Description:Inhibition of [3H]DAGO binding to trat brain opioid receptor mu in P2 membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 627nMAssay Description:Displacement of [125I]-DAMGO from mouse Flag-tagged mu-opioid receptor expressed in HEK293 cell membranes after 60 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 854nMAssay Description:Agonist activity at mu-opioid receptor in guinea pig ileum assessed as inhibition of electrically induced contractionsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Tested for agonist activity against mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences
Curated by ChEMBL
National Institute Of Environmental Health Sciences
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Agonist activity at rat mu-opioid receptor expressed in HEK293 cells co-expressing Rluc2-EPAC-GFP10 biosenser assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
