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Found 2 Enz. Inhib. hit(s) with Target = 'Proprotein convertase subtilisin/kexin type 9' and Ligand = 'BDBM200318'
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM200318(US9227956, 3)
Affinity DataIC50:  780nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM200318(US9227956, 3)
Affinity DataIC50:  800nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent