BDBM200318 US9227956, 3
SMILES Cc1cnc2n(nnc2c1)-c1ccc(cc1)C(=O)N([C@@H]1CCCNC1)c1ncccc1Cl
InChI Key InChIKey=CZJIXNHTVSHQML-GOSISDBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 200318
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of dofetilide binding to human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair