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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50343911'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50343911(3-Nitro-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)py...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-induced PGE2 production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50343911(3-Nitro-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)py...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of purified COX2 assessed as formation of oxidized TMPD during reduction og PGG2 to PGH2 preincubated for 15 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed