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Found 1 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM507762'
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM507762(7-chloro-4-(dimethylamino)-1-phenyl- quinazolin-2(...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PRMT5 in human HCT116-MTAP null cells assessed as reduction in symmetric dimethylation of arginine using SAM as substrate incubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed