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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase ATR' and Ligand = 'BDBM50459018'
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50459018(CHEMBL4166405)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of ATR in human HT-29 cells assessed as reduction in Chk1 phosphorylation at Ser-345 residue after 60 mins in presence of 4-nitroquinoline...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50459018(CHEMBL4166405)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of ATR in human HT-29 cells measured after 1 hr by Hoechst 33258 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed