Found 8 Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50039197'
Affinity DataKi: 2.20nMAssay Description:Inhibition of Phosphodiesterase 2 from pig coronary arteryMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Tested for its binding affinity towards sigma-1 site in rat brain, using [3H]-(+)-SKF- 10047 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 46.5nMAssay Description:Binding affinity against Sigma receptor type 1 was determined by the displacement of [3H]pentazocine radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Displacement of [3H]-PTZ from sigma1 receptor in guinea pig brain membranes after 150 mins in presence of 1 mM DPH by liquid scintillation counting m...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataKi: 67nMAssay Description:Displacement of [3H]-PTZ from sigma1 receptor in guinea pig brain membranes after 150 mins in presence of 250 uM DPH by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataKi: 151nMAssay Description:Displacement of [3H]-PTZ from sigma1 receptor in guinea pig brain membranes after 150 mins in presence of 1 mM DPH by liquid scintillation counting m...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair