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Found 4 Enz. Inhib. hit(s) with Target = 'Transcriptional activator protein LuxR' and Ligand = 'BDBM50266165'
TargetTranscriptional activator protein LuxR(Vibrio fischeri)
Larkin University

Curated by ChEMBL
LigandPNGBDBM50266165((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Affinity DataIC50:  600nMAssay Description:Antagonist activity at Aliivibrio fischeri ES114 LuxR after 4 to 8 hrs by luminescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LuxR(Vibrio fischeri (strain ATCC 700601 / ES114))TBA
LigandPNGBDBM50266165((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Affinity DataIC50:  600nMAssay Description:Antagonist activity against LuxR mediated quorum sensing system in Vibrio fischeri ES114 expressing luxI assessed as decrease in luminescence intensi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscriptional activator protein LuxR(Vibrio fischeri (strain ATCC 700601 / ES114))TBA
LigandPNGBDBM50266165((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Affinity DataIC50:  610nMAssay Description:Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LuxR(Vibrio fischeri)
Larkin University

Curated by ChEMBL
LigandPNGBDBM50266165((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Affinity DataIC50:  610nMAssay Description:Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed