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Found 3 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50308188'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308188(2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyri...)
Affinity DataIC50:  73nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308188(2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyri...)
Affinity DataIC50:  73nMAssay Description:Inhibition of recombinant VEGFR2 using poly(Glu,Tyr)4 as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig

Curated by ChEMBL
LigandPNGBDBM50308188(2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyri...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed