Found 99 Enz. Inhib. hit(s) with all data for entry = 50016959 TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity towards KDM4A (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetLysine-specific demethylase 5B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity towards KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Inhibition of N-terminal GST-tagged human KDM4C (2 to 372 residues) expressed in baculovirus-infected Sf9 cells measured by high-throughput mass spec...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 420nMAssay Description:Inhibition of His6-tagged recombinant human KDM4A (1 to 359 residues) measured by fluorescence polarization based competitive binding assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 420nMAssay Description:Inhibition of His6-tagged recombinant human KDM4A (1 to 359 residues) measured by fluorescence polarization based competitive binding assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 420nMAssay Description:Inhibition of His6-tagged recombinant human KDM4A (1 to 359 residues) measured by fluorescence polarization based competitive binding assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of KDM4C (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM4A (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human KDM4B (1 to 500 residues) measured by antibody-based fluorometric assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human KDM5B using H3(1-21)K4-Me3-GGK Biotin as substrate and measured by Alphascreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4D(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of KDM4D (unknown origin) measured by AlphaLisa-based screening assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of KDM5D (unknown origin) in presence of 4 uM 2-OGMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of KDM5C (unknown origin) in presence of 4 uM 2-OGMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of KDM5A (unknown origin) in presence of 4 uM 2-OGMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of KDM5B (unknown origin) in presence of 4 uM 2-OGMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus-infected Sf9 cells using ARTKQTARK(Me3)STGGK...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of KDM4A (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of KDM4C (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of KDM4B (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4A (unknown origin) using H3K9me3 as substrate and measured by LANCE TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4B (unknown origin) using H3K9me3 as substrate and measured by LANCE TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9me3 as substrate and measured by LANCE TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4D(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4D (unknown origin) using H3K9me3 as substrate and measured by LANCE TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of KDM4C (1 to 352 residues) (unknown origin) using biotin-tagged histone H3 (residues 1-21) lysine 9 trimethylated peptide as substrate i...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of KDM5C (unknown origin) measured by RapidFire mass spectrometry (RFMS)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of KDM4C (unknown origin) measured by RapidFire mass spectrometry (RFMS)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4D(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of KDM4D (unknown origin) measured by RapidFire mass spectrometry (RFMS)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of KDM5A (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of KDM5A (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of KDM5A (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human KDM4E heterogenously expressed in Escherichia coli using biotin-H3(1-15)K9Me3 as substrate and measured by Alphascreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of KDM5A (unknown origin) measured by ELISA assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of KDM4A in human MIA PaCa-2 cells assessed as induction of H3K9me3 measured by immunofluorescence assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of KDM2A in human MIA PaCa-2 cells assessed as induction of H3K36me2 measured by immunofluorescence assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of KDM4A in human MIA PaCa-2 cells assessed as induction of H3K9me3 measured by immunofluorescence assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of KDM4A in human MIA PaCa-2 cells assessed as induction of H3K9me3 measured by immunofluorescence assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of KDM2A in human MIA PaCa-2 cells assessed as induction of H3K36me2 measured by immunofluorescence assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of KDM2A in human MIA PaCa-2 cells assessed as induction of H3K36me2 measured by immunofluorescence assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of N-terminal His6-tagged human KDM4E (1 to 337 residues) measured by ELISA assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human KDM4A (1 to 350 residues) measured by ELISA assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of KDM4B (unknown origin) measured by ELISA assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4D(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of His-tagged human KDM4D (1 to 350 residues) measured by ELISA assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of KDM4C (unknown origin) measured by ELISA assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of KDM6B (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of KDM6B (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of KDM6B (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4D(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of KDM4D (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 558nMAssay Description:Inhibition of KDM5C (unknown origin) in presence of 300 uM 2-OGMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 558nMAssay Description:Inhibition of KDM5B (unknown origin) in presence of 300 uM 2-OGMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 558nMAssay Description:Inhibition of KDM5A (unknown origin) in presence of 300 uM 2-OGMore data for this Ligand-Target Pair
