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Target
Chymotrypsin-like elastase family member 2A
Ligand
BDBM50060338
Substrate
n/a
Meas. Tech.
ChEMBL_156952 (CHEMBL762662)
IC50
>10000000±n/a nM
Citation
 Buynak, JD; Rao, AS; Ford, GP; Carver, C; Adam, G; Geng, B; Bachmann, B; Shobassy, S; Lackey, S 7-alkylidenecephalosporin esters as inhibitors of human leukocyte elastase. J Med Chem 40:3423-33 (1997) [PubMed]  Article 
Target
Name:
Chymotrypsin-like elastase family member 2A
Synonyms:
CEL2A_PIG | CELA2A | ELA2 | ELA2A | Elastase 2A | Elastase-2 | Elastase-2A | Pancreatic elastase
Type:
PROTEIN
Mol. Mass.:
28705.23
Organism:
Sus scrofa
Description:
ChEMBL_156951
Residue:
269
Sequence:
MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIANN
  
Inhibitor
Name:
BDBM50060338
Synonyms:
3-Acetoxymethyl-5,5,8-trioxo-7-[1-phenyl-meth-(Z)-ylidene]-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester | CHEMBL114107
Type:
Small organic molecule
Emp. Form.:
C30H25NO7S
Mol. Mass.:
543.587
SMILES:
CC(=O)OCC1=C(N2C(\C(=C/c3ccccc3)C2=O)S(=O)(=O)C1)C(=O)OC(c1ccccc1)c1ccccc1 |t:5|
Structure:
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