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Target
Kappa-type opioid receptor
Ligand
BDBM50094634
Substrate
n/a
Meas. Tech.
ChEMBL_145391 (CHEMBL750081)
Ki
1058±n/a nM
Citation
 Shinkai, H; Ito, T; Iida, T; Kitao, Y; Yamada, H; Uchida, I 4-Aminoquinolines: novel nociceptin antagonists with analgesic activity. J Med Chem 43:4667-77 (2001) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50094634
Synonyms:
CHEMBL140979 | N-(4-Amino-2-methyl-quinolin-6-yl)-2-(4-ethyl-phenoxymethyl)-benzamide | N-(4-amino-2-methylquinolin-6-yl)-2-((4-ethylphenoxy)methyl)benzamide
Type:
Small organic molecule
Emp. Form.:
C26H25N3O2
Mol. Mass.:
411.4956
SMILES:
CCc1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1
Structure:
Search PDB for entries with ligand similarity: