Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50613242
Substrate
n/a
Meas. Tech.
ChEMBL_2291527
Ki
0.430000±n/a nM
Citation
 Abatematteo, FS; Majellaro, M; Montsch, B; Prieto-Díaz, R; Niso, M; Contino, M; Stefanachi, A; Riganti, C; Mangiatordi, GF; Delre, P; Heffeter, P; Sotelo, E; Abate, C Development of Fluorescent 4-[4-(3 J Med Chem 66:3798-3817 (2023) [PubMed] 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50613242
Synonyms:
CHEMBL5271751
Type:
Small organic molecule
Emp. Form.:
C24H28N2O
Mol. Mass.:
360.4919
SMILES:
C(CCn1ccc2ccccc12)CN1CCC2(CC1)OCc1ccccc21
Structure:
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