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Target
Histone deacetylase 1
Ligand
BDBM50211063
Substrate
n/a
Meas. Tech.
ChEMBL_434813 (CHEMBL917041)
IC50
1880±n/a nM
Citation
 Pérez-Balado, C; Nebbioso, A; Rodríguez-Graña, P; Minichiello, A; Miceli, M; Altucci, L; de Lera, AR Bispyridinium dienes: histone deacetylase inhibitors with selective activities. J Med Chem 50:2497-505 (2007) [PubMed]  Article 
Target
Name:
Histone deacetylase 1
Synonyms:
Cereblon/Histone deacetylase 1 | HD1 | HDAC1 | HDAC1_HUMAN | Histone deacetylase 1 (HDAC1) | Human HDAC1 | RPD3L1
Type:
Enzyme
Mol. Mass.:
55090.27
Organism:
Homo sapiens (Human)
Description:
Q13547
Residue:
482
Sequence:
MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA
  
Inhibitor
Name:
BDBM50211063
Synonyms:
1-(oct-7-enyl)-3-{12-[3-(pent-4-enyl)pyridinium-1-yl]dodecyl}-pyridinium chloride iodide | CHEMBL226556
Type:
Small organic molecule
Emp. Form.:
C35H56N2
Mol. Mass.:
504.8314
SMILES:
C=CCCCCCC[n+]1cccc(CCCCCCCCCCCC[n+]2cccc(CCCC=C)c2)c1
Structure:
Search PDB for entries with ligand similarity: