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Target
Proto-oncogene tyrosine-protein kinase Src
Ligand
BDBM50196879
Substrate
n/a
Meas. Tech.
ChEMBL_1618939 (CHEMBL3861108)
IC50
39100±n/a nM
Citation
 Wang, YD; Bao, XQ; Xu, S; Yu, WW; Cao, SN; Hu, JP; Li, Y; Wang, XL; Zhang, D; Yu, SS A Novel Parkinson's Disease Drug Candidate with Potent Anti-neuroinflammatory Effects through the Src Signaling Pathway. J Med Chem 59:9062-9079 (2016) [PubMed]  Article 
Target
Name:
Proto-oncogene tyrosine-protein kinase Src
Synonyms:
Neuronal proto-oncogene tyrosine-protein kinase Src | Proto-oncogene c-Src | SRC_MOUSE | Src | Tyrosine-protein kinase SRC | pp60c-src (p60-Src)
Type:
Protein
Mol. Mass.:
59894.66
Organism:
Mus musculus (Mouse)
Description:
P05480
Residue:
535
Sequence:
MGSNKSKPKDASQRRRSLEPSENVHGAGGAFPASQTPSKPASADGHRGPSAAFVPPAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
  
Inhibitor
Name:
BDBM50196879
Synonyms:
CHEMBL3978735
Type:
Small organic molecule
Emp. Form.:
C13H19NO5
Mol. Mass.:
269.2937
SMILES:
COc1cc(OC)c(CN[C@@H](C)C(O)=O)c(OC)c1 |r|
Structure:
Search PDB for entries with ligand similarity: