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Found 80 with Last Name = 'törmäkangas' and Initial = 'o'
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309987(N-((S)-1-(3-(3-chloro-4-cyano-2-methylphenyl)-1H-p...)
Affinity DataKi:  3nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508526(N-((S)-1-(3-(3-chloro-4-cyano-2-methylphenyl)-1H-p...)
Affinity DataKi:  3nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309973((S)-N-(1-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-...)
Affinity DataKi:  6nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309973((S)-N-(1-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-...)
Affinity DataKi:  6nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309982((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  8nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309982((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  8nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508530((R)-N-(2-(3-(4-cyano-3,5-difluorophenyl)-1H-pyrazo...)
Affinity DataKi:  12nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309988((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  12nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309990((R)-N-(2-(3-(4-cyano-3,5-difluorophenyl)-1H-pyrazo...)
Affinity DataKi:  12nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309988((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  12nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508521((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  13nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309981((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  13nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309979(N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  14nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508534((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  14nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309995((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  14nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508519(N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  14nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309976((S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-p...)
Affinity DataKi:  16nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309992((S)-N-{1-[3-(3-Chloro-4-cyano-5-fluorophenyl)-1H-p...)
Affinity DataKi:  16nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309992((S)-N-{1-[3-(3-Chloro-4-cyano-5-fluorophenyl)-1H-p...)
Affinity DataKi:  16nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309976((S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-p...)
Affinity DataKi:  16nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309983(N-((R)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  17nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508523((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  17nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309980(N-(2-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-yl)e...)
Affinity DataKi:  18nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309980(N-(2-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-yl)e...)
Affinity DataKi:  18nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309993((S)-N-(1-(3-(3-chloro-4-cyano-5-fluorophenyl)-1H-p...)
Affinity DataKi:  25nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309993((S)-N-(1-(3-(3-chloro-4-cyano-5-fluorophenyl)-1H-p...)
Affinity DataKi:  25nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309978(N-(2-(3-(3,4-dicyanophenyl)-1H-pyrazol-1-yl)ethyl)...)
Affinity DataKi:  27nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309978(N-(2-(3-(3,4-dicyanophenyl)-1H-pyrazol-1-yl)ethyl)...)
Affinity DataKi:  27nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309986((R)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  29nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309986((R)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  29nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309991((S)-N-{1-[3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  31nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309991((S)-N-{1-[3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  31nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309985(N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  38nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508524(N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataKi:  38nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309976((S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-p...)
Affinity DataKi:  40nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)
Affinity DataKi:  40nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309989((S)-3-acetyl-N-(2-(3-(4-cyano-3,5-difluorophenyl)-...)
Affinity DataKi:  40nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309994(US9657003, Bicalutamide)
Affinity DataKi:  40nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309972(N-(2-(5-(3,4-dichlorophenyl)furan-2-yl)ethyl)-3-(m...)
Affinity DataKi:  62nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508515(N-(2-(5-(3,4-dichlorophenyl)furan-2-yl)ethyl)-3-(m...)
Affinity DataKi:  62nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508526(N-((S)-1-(3-(3-chloro-4-cyano-2-methylphenyl)-1H-p...)
Affinity DataIC50:  11nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309987(N-((S)-1-(3-(3-chloro-4-cyano-2-methylphenyl)-1H-p...)
Affinity DataIC50:  11nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309988((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataIC50:  29nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309988((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataIC50:  29nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508530((R)-N-(2-(3-(4-cyano-3,5-difluorophenyl)-1H-pyrazo...)
Affinity DataIC50:  33nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309990((R)-N-(2-(3-(4-cyano-3,5-difluorophenyl)-1H-pyrazo...)
Affinity DataIC50:  33nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309973((S)-N-(1-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-...)
Affinity DataIC50:  34nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309973((S)-N-(1-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-...)
Affinity DataIC50:  34nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309992((S)-N-{1-[3-(3-Chloro-4-cyano-5-fluorophenyl)-1H-p...)
Affinity DataIC50:  42nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508534((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...)
Affinity DataIC50:  42nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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