BDBM174917 US9096593, P-1646

SMILES COc1ncc(CNc2ccc(Cc3c[nH]c4ncc(cc34)C(F)(F)F)c(F)n2)cc1F

InChI Key InChIKey=QYLNYSKRQDLKES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 174917   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM174917(US9096593, P-1646)
Affinity DataIC50: <100nMpH: 7.5 T: 2°CAssay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of Flt-3 kinase activity, where inhibition of phosphoryla...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM174917(US9096593, P-1646)
Affinity DataIC50: <100nMpH: 7.5 T: 2°CAssay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of Fms kinase activity, where inhibition of phosphorylati...More data for this Ligand-Target Pair
In DepthDetails US Patent