BDBM24307 Letrozole derivative, 40a R-(+)::{2-bromo-4-[(R)-(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]phenyl} sulfamate

SMILES NS(=O)(=O)Oc1ccc(cc1Br)[C@@H](c1ccc(cc1)C#N)n1cncn1

InChI Key InChIKey=SGRBZPZPWNVVPZ-MRXNPFEDSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24307   

TargetAromatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM24307(Letrozole derivative, 40a R-(+) | {2-bromo-4-[(R)-...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM24307(Letrozole derivative, 40a R-(+) | {2-bromo-4-[(R)-...)
Affinity DataIC50:  4.63E+3nMAssay Description:Inhibition of STS activity (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed