BDBM365174 4-(3-(3-chlorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- triazaacenaphthylen-7-yl)-N- (1-methyl-1H-pyrazol-5- yl)pyrimidin-2-amine::US10278975, Compound I-88 S::US11376260, Example I-88S::US9867833, Compound I-88(R)
SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OC[C@@H](Cc3cccc(Cl)c3)c3nnc(c1)n23
InChI Key InChIKey=SYCYKCJYHIDUFW-MRXNPFEDSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 365174
Affinity DataIC50: 6.36nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 6.36nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair