BDBM450998 US10676470, Compound 44::US11332464, Compound 44

SMILES NCCCC[C@H](NC(=O)C1CCCC1)C(=O)c1ccccn1

InChI Key InChIKey=UTTIJDOISNRHGN-HNNXBMFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450998   

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM450998(US10676470, Compound 44 | US11332464, Compound 44)
Affinity DataIC50: >250nMAssay Description:Buffer: pH=7.5, 100 mM Tris-HCl, 75 mM NaCl, 2.5 mM CaCl2, 10 mM cysteine, 1% DMSO after all additions. Protein: 0.1 nM Kgp, isolated from culture of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM450998(US10676470, Compound 44 | US11332464, Compound 44)
Affinity DataIC50: >250nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent