BDBM50181876 CHEMBL371861::N-(4'-fluoro-biphenyl-4-carbonyl)-3-nitro-4-(2-phenylsulfanyl-ethylamino)-benzenesulfonamide::N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITRO-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE
SMILES [O-][N+](=O)c1cc(ccc1NCCSc1ccccc1)S(=O)(=O)NC(=O)c1ccc(cc1)-c1ccc(F)cc1
InChI Key InChIKey=SWGIDRBGIJDBQO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50181876
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Mus musculus)
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of binding of wild type mBIMBH3 peptide to mouse adenosine A1 receptor by surface plasmon resonance competition experimentMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Bcl-XL in presence of 1% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Binding affinity to Bcl2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Inhibitory activity against Bcl-XL in presence of alpha1 acid glycoprotein from 1% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Bcl-XL in presence of HSA from 1% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory activity against Bcl-XL in presence of HSA3 from 1% human serumMore data for this Ligand-Target Pair