BDBM50322341 CHEMBL1171803::Methyl4-(2-((R)-3-((4-chloro-2-(trifluoromethyl)phenylcarbamoyloxy)methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-1-yl)acetamido)-6-methylhept-2-enoate

SMILES COC(=O)\C=C\[C@H](CC(C)C)NC(=O)CN1c2ccccc2C(=N[C@H](COC(=O)Nc2ccc(Cl)cc2C(F)(F)F)C1=O)c1ccccc1

InChI Key InChIKey=MWWJVCKMVKBUFV-CMSSCCRCSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322341   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universit£

Curated by ChEMBL
LigandPNGBDBM50322341(CHEMBL1171803 | Methyl4-(2-((R)-3-((4-chloro-2-(tr...)
Affinity DataKi:  870nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
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Curated by ChEMBL
LigandPNGBDBM50322341(CHEMBL1171803 | Methyl4-(2-((R)-3-((4-chloro-2-(tr...)
Affinity DataKi:  2.22E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 after 10 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50322341(CHEMBL1171803 | Methyl4-(2-((R)-3-((4-chloro-2-(tr...)
Affinity DataKi:  3.91E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50322341(CHEMBL1171803 | Methyl4-(2-((R)-3-((4-chloro-2-(tr...)
Affinity DataKi: >1.50E+5nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed