BDBM50322422 CHEMBL1173445::Largazole

SMILES CCCCCCCC(=O)SCC\C=C\[C@@H]1CC(=O)NCc2nc(cs2)C2=N[C@@](C)(CS2)C(=O)N[C@@H](C(C)C)C(=O)O1

InChI Key InChIKey=AXESYCSCGBQJBL-SZPBEECKSA-N

Data  44 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322422   

TargetHistone deacetylase 3(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)
Affinity DataIC50:  670nMAssay Description:Inhibition of HDAC3 (unknown origin) using MAZ1600 and MAZ1675 as substrate assessed as fluorogenic release of 7-amino-4-methylcoumarin from substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed