BDBM50322422 CHEMBL1173445::Largazole
SMILES CCCCCCCC(=O)SCC\C=C\[C@@H]1CC(=O)NCc2nc(cs2)C2=N[C@@](C)(CS2)C(=O)N[C@@H](C(C)C)C(=O)O1
InChI Key InChIKey=AXESYCSCGBQJBL-SZPBEECKSA-N
Data 44 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50322422
TargetHistone deacetylase 6(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of recombinant human HDAC6 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of recombinant human HDAC10 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC11 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 859nMAssay Description:Inhibition of recombinant human HDAC3 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human HDAC1 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC5 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC7 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC9 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of recombinant human HDAC2 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institute Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC4 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair