BDBM50322422 CHEMBL1173445::Largazole
SMILES CCCCCCCC(=O)SCC\C=C\[C@@H]1CC(=O)NCc2nc(cs2)C2=N[C@@](C)(CS2)C(=O)N[C@@H](C(C)C)C(=O)O1
InChI Key InChIKey=AXESYCSCGBQJBL-SZPBEECKSA-N
Data 44 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50322422
TargetHistone deacetylase 3(Homo sapiens (Human))
Chinese National Center For Drug Screening
Curated by ChEMBL
Chinese National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Chinese National Center For Drug Screening
Curated by ChEMBL
Chinese National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening
Curated by ChEMBL
Chinese National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(epsilon-acetyl)-AMC as substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair