Compile Data Set for Download or QSAR
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Found 90 with Last Name = 'rettie' and Initial = 'ae'
TargetCytochrome P450 2C9(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158460((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)
Affinity DataKi:  19nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataKi:  26nMAssay Description:Inhibition of human placental microsome aromatase using [3H]androstenedione as substrate preincubated for 32 mins in presence of NADPH followed by su...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158458((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-dimethylphe...)
Affinity DataKi:  33nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158458((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-dimethylphe...)
Affinity DataKi:  40nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158464((2-ethylbenzofuran-3-yl)(4-methoxy-3,5-dimethylphe...)
Affinity DataKi:  250nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158470(2,6-dibromo-4-((2-ethylbenzofuran-3-yl)(hydroxy)me...)
Affinity DataKi:  300nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158463((3,5-dibromo-4-methoxyphenyl)(2-ethylbenzofuran-3-...)
Affinity DataKi:  370nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158467(2-(3,5-dibromo-4-hydroxyphenyl)-1-(2-ethylbenzofur...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158469((3,5-dibromo-4-hydroxyphenyl)(2-methylbenzofuran-3...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158457((4-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanon...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158462((4-(dimethylamino)phenyl)(2-ethylbenzofuran-3-yl)m...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158460((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158466((4-methoxyphenyl)(2-methylbenzofuran-3-yl)methanon...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158459((3-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanon...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158465((4-hydroxy-3,5-diiodophenyl)(2-methylbenzofuran-3-...)
Affinity DataKi:  7.20E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158461((2,6-dichloropyridin-4-yl)(2-ethylbenzofuran-3-yl)...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158468(CHEMBL390613 | cyclohexyl(2-methylbenzofuran-3-yl)...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527964(CHEMBL4564920)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527968(CHEMBL4590991)
Affinity DataIC50:  200nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  200nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527961(CHEMBL4435658)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527965(CHEMBL4447108)
Affinity DataIC50:  400nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527966(CHEMBL4466562)
Affinity DataIC50:  500nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527960(CHEMBL4568702)
Affinity DataIC50:  700nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527967(CHEMBL4554028)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527962(CHEMBL4442292)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527964(CHEMBL4564920)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527968(CHEMBL4590991)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527965(CHEMBL4447108)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527961(CHEMBL4435658)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527966(CHEMBL4466562)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50106744(1H-1,2,3-benzotriazol-1-amine | CHEMBL101168)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527960(CHEMBL4568702)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527962(CHEMBL4442292)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527967(CHEMBL4554028)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4F8(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate preincubated with NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of CYP1A2 in human pooled liver microsomes using phenacetin as substrate preincubated with NADPH for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4F12(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of recombinant human CYP4F12 expressed in baculovirus infected insect cells using Luc-BE as substrate preincubated with NADPH for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of CYP2B6 in human pooled liver microsomes using bupropion as substrate preincubated with NADPH for 30 mins followed by substrate addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of CYP2C8 in human pooled liver microsomes using amodiaquine as substrate preincubated with NADPH for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4F8(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate after 10 mins in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  1.28E+5nMAssay Description:Inhibition of CYP3A4/5 in human pooled liver microsomes using midazolam as substrate preincubated with NADPH for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4Z1(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50106744(1H-1,2,3-benzotriazol-1-amine | CHEMBL101168)
Affinity DataIC50:  1.54E+5nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 4F12(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  1.67E+5nMAssay Description:Inhibition of recombinant human CYP4F12 expressed in baculovirus infected insect cells using Luc-BE as substrate after 10 mins in presence of NADPH b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4A11(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  1.79E+5nMAssay Description:Inhibition of recombinant human CYP4A11 expressed in baculovirus infected insect cells using Luc-4A as substrate preincubated with NADPH for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4F3(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  1.87E+5nMAssay Description:Inhibition of recombinant human CYP4F3B expressed in baculovirus infected insect cells using Luc-4F2/3 as substrate after 10 mins in presence of NADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4F2(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  2.12E+5nMAssay Description:Inhibition of recombinant human CYP4F2 expressed in baculovirus infected insect cells using Luc-4F2/3 as substrate after 10 mins in presence of NADPH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 4F3(Homo sapiens)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50527963(CHEMBL4557940)
Affinity DataIC50:  2.13E+5nMAssay Description:Inhibition of recombinant human CYP4F3B expressed in baculovirus infected insect cells using Luc-4F2/3 as substrate preincubated with NADPH for 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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