Found 399 with Last Name = 'ullah' and Initial = 's' TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate ...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University
Curated by ChEMBL
Pusan National University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate incubated for 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HDAC2 using FLUOR-DE-LYS-Green as substrate incubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University
Curated by ChEMBL
Pusan National University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate incubated for 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human HDAC2 using FLUOR-DE-LYS-Green as substrate incubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human HDAC1 using SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by flu...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate ...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK2/CyclinA2 expressed in baculovirus infected Sf21 cells using histone H1 as substrate incuba...More data for this Ligand-Target Pair
3D Structure (crystal)TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant NPP1 expressed in COS-7 cell membrane at 100 uM using p-nitrophenyl thymidine monophosphate substrate incubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant NPP3 expressed in COS-7 cell membrane at 100 uM using p-nitrophenyl thymidine monophosphate substrate incubated for 3...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant His-tagged HDAC2 (1 to 582 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS Green as subst...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant NPP3 expressed in COS-7 cell membrane at 100 uM using p-nitrophenyl thymidine monophosphate substrate incubated for 3...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant His-tagged HDAC2 (1 to 582 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS Green as subst...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of NPP1 (unknown origin) transfected in COS7 cells using pNP-TMP as substrate incubated for 35 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 205nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of NPP3 (unknown origin) transfected in COS7 cells using pNP-TMP as substrate incubated for 35 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 214nMAssay Description:Inhibition of human NPP3 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair
TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 215nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human NPP3 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...More data for this Ligand-Target Pair
TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 234nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 10 mins followed by addition of substrate fluor De Lys green measured after 30 mins by fluores...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 10 mins followed by addition of substrate fluor De Lys green measured after 30 mins by fluores...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 254nMAssay Description:Inhibition of human NPP3 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 255nMAssay Description:Inhibition of human NPP3 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human HDAC1 using SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by flu...More data for this Ligand-Target Pair
TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 274nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate ...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human full length CDK2/cyclin A2 incubated for 10 mins by ADP-Glo reagent assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant His-tagged HDAC2 (1 to 582 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS Green as subst...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate ...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 369nMAssay Description:Inhibition of human NPP3 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate ...More data for this Ligand-Target Pair
TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Beijing University of Chemical Technology
Curated by ChEMBL
Beijing University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 381nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 387nMAssay Description:Inhibition of human NPP1 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant NPP1 expressed in COS-7 cell membrane at 100 uM using p-nitrophenyl thymidine monophosphate substrate incubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 422nMAssay Description:Inhibition of human NPP1 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 431nMAssay Description:Inhibition of human NPP1 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 441nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
