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Found 457 with Last Name = 'david' and Initial = 'l'
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254931(US9499542, 14 | US9675594, 14)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254931(US9499542, 14 | US9675594, 14)
Affinity DataKi:  0.100nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254929(US9499542, 12 | US9675594, 12)
Affinity DataKi:  0.5nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254929(US9499542, 12 | US9675594, 12)
Affinity DataKi:  2nMAssay Description:Inhibition of human wild type LRRK2 phosphorylation at ser935 transfected in HEK293 cells after 48 hrs by in-cell Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254928(US9499542, 11 | US9675594, 11)
Affinity DataKi:  3nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254919(US9499542, 2 | US9675594, 2)
Affinity DataKi:  4nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254918(US9499542, 1 | US9675594, 1)
Affinity DataKi:  6nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254918(US9499542, 1 | US9675594, 1)
Affinity DataKi:  6nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254928(US9499542, 11 | US9675594, 11)
Affinity DataKi:  12nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254919(US9499542, 2 | US9675594, 2)
Affinity DataKi:  13nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50250336(CHEMBL4068861)
Affinity DataKi:  13nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50250338(CHEMBL4077186)
Affinity DataKi:  23nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50250338(CHEMBL4077186)
Affinity DataKi:  23nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50250344(CHEMBL4088961)
Affinity DataKi:  23nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50250336(CHEMBL4068861)
Affinity DataKi:  27nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254921(US9499542, 4 | US9675594, 4)
Affinity DataKi:  31nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM254921(US9499542, 4 | US9675594, 4)
Affinity DataKi:  60nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557699(US11358971, Compound 1h | US11466027, Compound 1l)
Affinity DataKi:  63nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557699(US11358971, Compound 1h | US11466027, Compound 1l)
Affinity DataKi:  63nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50250344(CHEMBL4088961)
Affinity DataKi:  81nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445041(CHEMBL3098768 | US10195186, Example 48 | US9682967...)
Affinity DataKi:  84nM IC50:  88nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159226(US10195186, Example 46 | US9682967, 44)
Affinity DataKi:  84nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50250346(CHEMBL4075407)
Affinity DataKi:  95nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557694(US11358971, Compound 1c | US11466027, Compound 1e)
Affinity DataKi:  96nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557694(US11358971, Compound 1c | US11466027, Compound 1e)
Affinity DataKi:  96nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50250346(CHEMBL4075407)
Affinity DataKi:  124nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50469617(CHEMBL4066167)
Affinity DataKi:  136nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557693(US11358971, Compound 1b | US11466027, Compound 1d)
Affinity DataKi:  140nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557693(US11358971, Compound 1b | US11466027, Compound 1d)
Affinity DataKi:  140nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445042(CHEMBL3098767 | US10195186, Example 7 | US9682967,...)
Affinity DataKi:  162nM IC50:  170nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445042(CHEMBL3098767 | US10195186, Example 7 | US9682967,...)
Affinity DataKi:  162nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557667(US11358971, Compound 1a | US11466027, Compound 1c)
Affinity DataKi:  170nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557667(US11358971, Compound 1a | US11466027, Compound 1c)
Affinity DataKi:  170nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557701(US11358971, Compound 1j | US11466027, Compound 1n)
Affinity DataKi:  180nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557701(US11358971, Compound 1j | US11466027, Compound 1n)
Affinity DataKi:  180nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159232(US10195186, Example 47 | US9682967, 45)
Affinity DataKi:  190nM IC50:  200nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445055(CHEMBL3098744 | US10195186, Example 45 | US9682967...)
Affinity DataKi:  190nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSortilin(Mouse)
H. Lundbeck

US Patent
LigandPNGBDBM50445054(CHEMBL3098745 | US10195186, Example 1 | US9682967,...)
Affinity DataKi:  210nM IC50:  220nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
TargetSortilin(Mouse)
H. Lundbeck

US Patent
LigandPNGBDBM50445054(CHEMBL3098745 | US10195186, Example 1 | US9682967,...)
Affinity DataKi:  210nMAssay Description:The Sortilin assay was performed in total volume of 40 μl in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557698(US11358971, Compound 1g | US11466027, Compound 1k)
Affinity DataKi:  220nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM576021((R)-2-amino-3-[(7- isopropylthieno[3,2- b]pyridine...)
Affinity DataKi:  220nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557698(US11358971, Compound 1g | US11466027, Compound 1k)
Affinity DataKi:  220nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50250339(CHEMBL4092537)
Affinity DataKi:  225nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159140(US10195186, Example 18 | US9682967, 18)
Affinity DataKi:  229nM IC50:  240nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159140(US10195186, Example 18 | US9682967, 18)
Affinity DataKi:  229nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557702(US11358971, Compound 1k | US11466027, Compound 1o)
Affinity DataKi:  260nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM557702(US11358971, Compound 1k | US11466027, Compound 1o)
Affinity DataKi:  260nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM576017((R)-2-amino-3-[(7- ethylthieno[3,2-b]pyridine- 2- ...)
Affinity DataKi:  270nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159226(US10195186, Example 46 | US9682967, 44)
Affinity DataKi:  286nM IC50:  300nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM159213(US10195186, Example 44 | US9682967, 42)
Affinity DataKi:  286nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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