Compile Data Set for Download or QSAR
maximum 50k data
Found 21 with Last Name = 'kuhn' and Initial = 'p'
TargetAcetylcholinesterase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  6.90nM ΔG°:  -46.1kJ/molepH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM24710(6-chloro-2-methoxyacridin-9-amine | 9-Amino-6-Chlo...)
Affinity DataKi:  49nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM24709(6,9-Diamino-2-Ethoxyacridine | 7-ethoxyacridine-3,...)
Affinity DataKi:  490nM ΔG°:  -35.7kJ/molepH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM24710(6-chloro-2-methoxyacridin-9-amine | 9-Amino-6-Chlo...)
Affinity DataKi:  5.80E+3nM ΔG°:  -29.6kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition constants were calculated by assessment of the reduction in the formation of o-nitrophenol, as monitored by a spectrophotometric assay at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM24709(6,9-Diamino-2-Ethoxyacridine | 7-ethoxyacridine-3,...)
Affinity DataKi:  1.71E+4nM ΔG°:  -26.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition constants were calculated by assessment of the reduction in the formation of o-nitrophenol, as monitored by a spectrophotometric assay at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition constants were calculated by assessment of the reduction in the formation of o-nitrophenol, as monitored by a spectrophotometric assay at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM24709(6,9-Diamino-2-Ethoxyacridine | 7-ethoxyacridine-3,...)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition constants were calculated by assessment of the reduction in the formation of o-nitrophenol, as monitored by a spectrophotometric assay at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition constants were calculated by assessment of the reduction in the formation of o-nitrophenol, as monitored by a spectrophotometric assay at ...More data for this Ligand-Target Pair
TargetCoagulation factor XII(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM24710(6-chloro-2-methoxyacridin-9-amine | 9-Amino-6-Chlo...)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition constants were calculated by assessment of the reduction in the formation of o-nitrophenol, as monitored by a spectrophotometric assay at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Mus musculus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242406(CHEMBL448652 | SNEWIQPRLPQH)
Affinity DataIC50:  1.50E+4nMAssay Description:Binding affinity at mouse EphB2 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242407(CHEMBL525059 | SNQWIQPRLPQH)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242408(CHEMBL526907 | SNEWISPRLPQH)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242409(CHEMBL526325 | SNEWILPRLPQH)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242410(CHEMBL508644 | SNEWIQPKLPQH)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242411(CHEMBL504700 | SNEWIQPALPQH)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242412(CHEMBL451203 | SNEWIQPHLPQH)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242413(CHEMBL453443 | SNQWILPRLPQH)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242414(CHEMBL505364 | SNQWISPRLPQH)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242415(CHEMBL504627 | SNQWIGPALPQH)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242406(CHEMBL448652 | SNEWIQPRLPQH)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242416(CHEMBL508295 | TNYLFSPNGPIARAW)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity at human EphB2 receptor by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed