Affinity DataKi: 0.00300nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Binding affinity to human integrin alphaVbeta6 assessed as dissociation constant up to 48 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.0140nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0251nMAssay Description:Binding affinity to human integrin alphaVbeta6 assessed as dissociation constant up to 48 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.0316nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0398nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0398nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0398nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0398nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0398nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.107nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 0.160nM Kon: 4.90M-1s-1 Koff: 3.05E+4s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.174nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to human CB1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nM Kon: 0.00000207M-1s-1 Koff: 6.63E+3s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity to human CB1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to human CB1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Competitive inhibition of human RIP1 (1 to 375 residues) in presence of increasing ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Displacement of [3H]UR-3189 from integrin alpha2b beta3 receptor in resting human plateletMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity for non-peptide Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 1.73nM Kon: 0.0000109M-1s-1 Koff: 6.31E+3s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of integrin alphavbeta1 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human integrin alphaVbeta6 assessed as dissociation constant up to 48 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of HEK 293 cell adhesion to vitronectin by alpha V beta 3More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of HEK 293 cell adhesion to vitronectin by alpha V beta 3More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Competitive inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in LPC hydrolysis measured every 30 secs for 90 mins by Lin...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity for non-peptide Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as increase in calcium internalisation by FLIPR assayMore data for this Ligand-Target Pair