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Found 131 with Last Name = 'roux' and Initial = 'b'
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136383((4-chlorophenyl)(5-(3-chlorophenyl)tetrazolo[1,5-a...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136383((4-chlorophenyl)(5-(3-chlorophenyl)tetrazolo[1,5-a...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Geranylgeranylprotein transferase-I catalyzed incorporation of [3H]-GGPP into biotinYRASNRSCAIL peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50126335(6-[(R)-Amino-(4-chloro-phenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50126335(6-[(R)-Amino-(4-chloro-phenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301927(US9598396, Compound 4)
Affinity DataIC50:  0.933nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301928(US9598396, Compound 5)
Affinity DataIC50:  0.977nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136377(4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-(4-methyl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136375(6-[Amino-(4-chloro-phenyl)-(4-methyl-4H-[1,2,4]tri...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136385(C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-1-methy...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136379(4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-hydroxy-(...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136384((4-chlorophenyl)(5-(3-chlorophenyl)tetrazolo[1,5-a...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136384((4-chlorophenyl)(5-(3-chlorophenyl)tetrazolo[1,5-a...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Geranylgeranylprotein transferase-I catalyzed incorporation of [3H]-GGPP into biotinYRASNRSCAIL peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human HDAC11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136376(4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-(3-methyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136389(C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-[1,2,4]...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136384((4-chlorophenyl)(5-(3-chlorophenyl)tetrazolo[1,5-a...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of Geranylgeranylprotein transferase-I catalyzed incorporation of [3H]-GGPP into biotinYRASNRSCAIL peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136378(4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-hydroxy-(...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136380(4-(3-Chloro-phenyl)-6-[1-(4-chloro-phenyl)-1-(3-me...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50605273(CHEMBL5194902)
Affinity DataIC50:  4nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301932(US9598396, Compound 7)
Affinity DataIC50:  4.17nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human HDAC10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136386(C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-imidazo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136382(4-(3-Chloro-phenyl)-6-[1-(4-chloro-phenyl)-1-(4-me...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136381(4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-hydroxy-(...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136387(C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-imidazo...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50605259(CHEMBL5176505)
Affinity DataIC50:  7nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50605270(CHEMBL5207924)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50605281(CHEMBL5194957)
Affinity DataIC50:  9nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301932(US9598396, Compound 7)
Affinity DataIC50:  9.55nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301923(US9598396, Compound 1)
Affinity DataIC50:  14.1nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301929(US9598396, Compound 5a)
Affinity DataIC50:  15.8nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50605266(CHEMBL5171729)
Affinity DataIC50:  17nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301927(US9598396, Compound 4)
Affinity DataIC50:  17.4nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301931(US9598396, Compound 6)
Affinity DataIC50:  19.1nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301928(US9598396, Compound 5)
Affinity DataIC50:  19.5nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human HDAC11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136383((4-chlorophenyl)(5-(3-chlorophenyl)tetrazolo[1,5-a...)
Affinity DataIC50:  22nMAssay Description:Inhibition of Geranylgeranylprotein transferase-I catalyzed incorporation of [3H]-GGPP into biotinYRASNRSCAIL peptide at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136374(4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-hydroxy-(...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [3H]-FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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