TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataKi: 580nMAssay Description:Noncompetitive inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogeni...More data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataKi: 670nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataKi: 870nMAssay Description:Noncompetitive inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogeni...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetCorticotropin-releasing factor receptor 1(Monkey)
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataKi: 1.02E+3nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Noncompetitive inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogeni...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology
Curated by ChEMBL
Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair