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Found 40 with Last Name = 'voorbach' and Initial = 'm'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20722((1R,2R)-2-({4-[4-({[2-fluoro-5-(trifluoromethyl)ph...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20721((1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20716((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20727((1R,2R)-2-[(4-{4-[(2H-1,3-benzodioxol-5-ylcarbamoy...)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse DGAT1 using [1-14C]decanoyl-CoA substrate by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20718((1R,2R)-2-({4-[4-({[2-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20726((1R,2R)-2-({4-[4-({[4-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20724((1R,2R)-2-{[4-(4-{[(4-methoxyphenyl)carbamoyl]amin...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20719((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20720((1R,2R)-2-{[4-(4-{[(3-fluorophenyl)carbamoyl]amino...)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20726((1R,2R)-2-({4-[4-({[4-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20718((1R,2R)-2-({4-[4-({[2-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20719((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50:  17nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20721((1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino...)
Affinity DataIC50:  19nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20722((1R,2R)-2-({4-[4-({[2-fluoro-5-(trifluoromethyl)ph...)
Affinity DataIC50:  21nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20716((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50:  24nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20724((1R,2R)-2-{[4-(4-{[(4-methoxyphenyl)carbamoyl]amin...)
Affinity DataIC50:  28nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20725((1R,2R)-2-{[4-(4-{[(4-cyanophenyl)carbamoyl]amino}...)
Affinity DataIC50:  35nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20720((1R,2R)-2-{[4-(4-{[(3-fluorophenyl)carbamoyl]amino...)
Affinity DataIC50:  39nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394735(CHEMBL2165810)
Affinity DataIC50:  44nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20727((1R,2R)-2-[(4-{4-[(2H-1,3-benzodioxol-5-ylcarbamoy...)
Affinity DataIC50:  63nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20730((1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1...)
Affinity DataIC50:  73nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50:  78nMAssay Description:Inhibition of human DGAT1 expressed in human HeLa cells assessed as reduction in triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20728((1S,2S)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50:  96nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20729((1S,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50:  98nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394729(CHEMBL2165816)
Affinity DataIC50:  110nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20730((1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1...)
Affinity DataIC50:  207nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394730(CHEMBL2165815)
Affinity DataIC50:  250nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20725((1R,2R)-2-{[4-(4-{[(4-cyanophenyl)carbamoyl]amino}...)
Affinity DataIC50:  603nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20723((1R,2R)-2-({4-[4-({[3-(methylcarbamoyl)phenyl]carb...)
Affinity DataIC50:  994nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394736(CHEMBL2165809)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394733(CHEMBL2165812)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394734(CHEMBL2165811)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394732(CHEMBL2165813)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant DGAT2 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394728(CHEMBL2165817)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394727(CHEMBL2165818)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50394731(CHEMBL2165814)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human ERG by manual patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed