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Found 205 with Last Name = 'zhao' and Initial = 'lm'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataIC50:  2nMAssay Description:Inhibition of human ERG potassium channel transfected in CHO cells by automated patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM172452(US9090625, 4 | US9260450, 4 | US9938289, 4)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of recombinant human CYP19 expressed in baculovirus infected insect cells using MFC as substrate measured after 30 mins by fluorometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM311398(US10155763, Example 6)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535746(CHEMBL4519261)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 15 to 45 mins in presence of NADPHMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50197072(CHEMBL3948254)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of recombinant human microsomal CYP19 using MFC as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535750(CHEMBL4588407)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  11nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535747(CHEMBL4453060)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50197070(CHEMBL3944017)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human microsomal CYP19 using MFC as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535751(CHEMBL4574187)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50103642(4-(6-amino-5-bromo-2-(4-cyanophenylamino)pyrimidin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50015639(CHEMBL3260567 | USRE47141, Example 2)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535748(CHEMBL4474911)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535749(CHEMBL4464656)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535745(CHEMBL4576341)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535754(CHEMBL4543738)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50582100(CHEMBL5073811)
Affinity DataIC50:  20nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535756(CHEMBL4534375)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataIC50:  22nMAssay Description:Inhibition of human ERG potassium channel expressed in CHO cells by automated patch clamp electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535757(CHEMBL4553389)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535753(CHEMBL4516224)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535752(CHEMBL4447399)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597066(CHEMBL5202557)
Affinity DataIC50:  26nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597061(CHEMBL5176960)
Affinity DataIC50:  29nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597065(CHEMBL5196804)
Affinity DataIC50:  30nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597064(CHEMBL5200580)
Affinity DataIC50:  36nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597052(CHEMBL5195539)
Affinity DataIC50:  37nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597062(CHEMBL5204633)
Affinity DataIC50:  39nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597055(CHEMBL5199364)
Affinity DataIC50:  39nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597054(CHEMBL5202111)
Affinity DataIC50:  40nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597050(CHEMBL5175527)
Affinity DataIC50:  40nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50592720(CHEMBL5194948)
Affinity DataIC50:  41nMAssay Description:Inhibition of wild type HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597060(CHEMBL5183840)
Affinity DataIC50:  41nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597051(CHEMBL5185715)
Affinity DataIC50:  42nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535758(CHEMBL4533727)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50540175(CHEMBL4638285)
Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant GST-tagged human ALK5 expressed in baculovirus infected Sf9 insect cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50535755(CHEMBL4519255)
Affinity DataIC50:  43nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Yanbian University College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50:  43nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50508293(Doravirine | MK-1439 | Pifeltro)
Affinity DataIC50:  44nMAssay Description:Inhibition of wild type HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Yanbian University College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataIC50:  45nMAssay Description:Inhibition of CYP3A4T (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597056(CHEMBL5173442)
Affinity DataIC50:  45nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597037(CHEMBL5191003)
Affinity DataIC50:  45nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597038(CHEMBL5184248)
Affinity DataIC50:  46nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50:  47nMAssay Description:Inhibition of GST-tagged ALK5 kinase domain (unknown origin) using GST-tagged SMAD3 as substrate in presence of [33P] gammaATP by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597059(CHEMBL5197364)
Affinity DataIC50:  50nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597058(CHEMBL5201454)
Affinity DataIC50:  50nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597053(CHEMBL5209478)
Affinity DataIC50:  50nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50597039(CHEMBL5194488)
Affinity DataIC50:  52nMAssay Description:Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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