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Found 74 with Last Name = 'zink' and Initial = 'dl'
LigandPNGBDBM50287709((E)-3-Carboxy-2-(16-sulfooxy-hexadecyl)-pent-2-ene...)
Affinity DataKi:  4.5nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferase with respect to FPPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292415(CHEMBL504845 | Zaragozic Acid B)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50038096((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.290nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292333(CHEMBL505374 | zaragozic acid C)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292413(CHEMBL502210 | Zaragozic Acid D2)
Affinity DataIC50:  2nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287707((E)-3-Carboxy-2-(16-hydroxy-hexadecyl)-pent-2-ened...)
Affinity DataIC50:  3.30nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50: <4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292414(CHEMBL502872 | Zaragozic Acid D)
Affinity DataIC50:  6nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406470(Kibdelomycin)
Affinity DataIC50:  9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50287708((E)-3-Methoxycarbonyl-2-(16-sulfooxy-hexadecyl)-pe...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287709((E)-3-Carboxy-2-(16-sulfooxy-hexadecyl)-pent-2-ene...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50038118((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)
Affinity DataIC50:  200nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285550(3-Carboxy-2-((E)-6,8-dimethyl-9-phenyl-non-6-enyl)...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50486087(Kibdelomycin A)
Affinity DataIC50:  400nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366855(CHEMBL525803 | Chloropeptin)
Affinity DataIC50:  400nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)
Affinity DataIC50:  500nMAssay Description:Inhibition of disintegration activity of HIV1 integrase catalytic core domain (50 to 212)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)
Affinity DataIC50:  500nMAssay Description:Inhibition of disintegration activity of HIV1 intact integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478734(CHEMBL448564)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478738(CHEMBL507121)
Affinity DataIC50:  600nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285549(3-Carboxy-2-((E)-6,8-dimethyl-11-phenyl-undec-10-e...)
Affinity DataIC50:  767nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478735(CHEBI:65655 | COMPLESTATINS A)
Affinity DataIC50:  800nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124971((2R,3S)-5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetra...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478740(CHEBI:65656 | COMPLESTATIN B)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 2(Staphylococcus aureus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50483833(Platensimycin A1)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of Staphylococcus aureus FASF assessed as [2-14C]-malonyl CoA incorporation after 90 mins by cell free-based scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124966((8R,9R)-2,4,5-Trihydroxy-8,9-dimethyl-1-((2S,3R)-5...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of integration activity of HIV1 intact integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478736(CHEMBL505739)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124971((2R,3S)-5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetra...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123449(CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366855(CHEMBL525803 | Chloropeptin)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50281513(Acetic acid 9-((S)-1-acetoxy-3-methyl-butyl)-8-met...)
Affinity DataIC50:  5.00E+3nMAssay Description:Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478734(CHEMBL448564)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50071242(Acetic acid (6aR,6bS,9S,10aR,12aS)-5-hydroxy-1,3-d...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478739(CHEMBL448271)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124964(6,8'-Dihydroxy-5,8,5',6'-tetramethoxy-2,3,2',3'-te...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478738(CHEMBL507121)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50:  8.40E+3nMAssay Description:Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285551(3-Carboxy-2-hexadecyl-3-hydroxy-pentanedioic acid ...)
Affinity DataIC50:  9.00E+3nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124966((8R,9R)-2,4,5-Trihydroxy-8,9-dimethyl-1-((2S,3R)-5...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478735(CHEBI:65655 | COMPLESTATINS A)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478740(CHEBI:65656 | COMPLESTATIN B)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50071241(Acetic acid (6aR,6bS,9S,10aR,12aS)-5-hydroxy-6b,10...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50281512(Acetic acid (S)-1-(4,11-dimethoxy-9-methyl-5-oxo-5...)
Affinity DataIC50:  2.10E+4nMAssay Description:Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478737(CHEMBL506051)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373178(PYCNIDIONE)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of stromelysin mediated beta-casein cleavageMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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