TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferase with respect to FPPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: <4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of disintegration activity of HIV1 integrase catalytic core domain (50 to 212)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of disintegration activity of HIV1 intact integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 767nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 2(Staphylococcus aureus)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of Staphylococcus aureus FASF assessed as [2-14C]-malonyl CoA incorporation after 90 mins by cell free-based scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of integration activity of HIV1 intact integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of stromelysin mediated beta-casein cleavageMore data for this Ligand-Target Pair